ABSTRACT
OBJECTIVE:To observe the clinical efficacy and safety of Qingjin huatan decoction for patients with AECOPD phlegm-heat obstructing lung. METHODS:120 patients with AECOPD phlegm-heat obstructing lung were divided into observation group and control group according to random number table,with 60 cases in each group. Control group received routine therapy as low-flow oxygen therapy,anti-infective,bronchiectasis,expectorant,etc.;observation group additionally received Qingjin huatan decoction(decocted by 400 ml pure water),tid,on the basis of control group. The levels of IL-8,IL-17,IL-23 and TNF-α were observed in 2 groups before and 7 d after treatment. Clinical efficacies and the occurrence of ADR were compared between 2 groups. RESULTS:Before treatment,there was no statistical significance in the levels of IL-8,IL-17,IL-23 and TNF-α between 2 groups (P>0.05). After treatment,the levels of IL-8,IL-17,IL-23 and TNF-α in observation group were significantly decreased and lower than in control group,with statistical significance (P0.05). Excellent rate of observation group was 95.00%,which was significantly higher than 78.95% of control group,with statistical significance(P0.05). CONCLUSIONS:Qingjin huatan decoction shows signifi-cant therapeutic efficacy in the treatment of AECOPD phlegm-heat obstructing lung,and can improve inflammatory factors with good safety.
ABSTRACT
Objective To evaluate the clinical effect ofXugu-Huoxue decoction combined with anatomical reduction and internal fixation with cannulated screws in patients with femoral neck fractures. Methods A total of 89 patients with femoral neck fractures were randomly divided into a control group and a Xugu-Huoxuegroup according to the random number table, with 46 in the control group and 45 in the Xugu-Huoxuegroup. The control group was treated with anatomical reduction and internal fixation with cannulated screws, while theXugu-Huoxuedecoction group was treated withXugu-Huoxuedecoction on the basis of the control group. The hemodynamics of the femoral vein was evaluated with color Doppler sonography. Hip function was rated with Harris hip score.ResultsAfter 12 months of treatment, the minimum diastolic velocity (12.0 ± 2.2 cm/svs.9.3 ± 2.0 cm/s;t=3.675,P<0.01), diameter (0.8 ± 0.3 cm vs. 0.6 ± 0.1 cm;t=3.675, P<0.01) and blood flow (1 123.4 ± 271.1 ml/minvs.901.2 ±121.1 ml/min;t=5.067,P<0.01) of the femoral vein in theXugu-Huoxuedecoction group were significantly increased than those in the control group. The rates of excellent or good in theXugu-Huoxuedecoction group and the control group was 86.7% (39/45) and 63.0% (29/46), respectively, with statistically significant difference (χ2=5.529,P=0.019). There were 2 patients (4.4%) with delayed fracture healing and 2 patients (4.4%) with femoral head necrosis in theXugu-Huoxuedecoction group, while 3 patients (6.5%) with delayed fracture healing, 5 patients (10.9%) with femoral head necrosis inthe control group, without statically significant difference (χ2value were 0.000, 0.572,P value were 1.000, 0.449, respectively).ConclusionXugu-Huoxue decoction combined with anatomical reduction and internal fixation with cannulated screwscan improve the fracture prognosis and the joint function in patients with femoral neck fractures.
ABSTRACT
Spasticity is a common complication of stroke.It may cause the function and ability of patients to be restricted significantly and affect the quality of life of both patients and their caregivers.The estimated prevalence of poststroke spasticity (PSS) is 19％ to 42.6％.PSS can be usually assessed by the Modified Ashworth Scale,Modified Tardieu Scale,and electromyography.Therapeutic methods of PSS include physical therapy and drug treatment.The treatment options should be individualized.